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MMV-667492

Chemical Structure : MMV-667492

CAS No.: 380877-02-1

MMV-667492 (MMV 667492;MMV667492)

Catalog No.: PC-70130Not For Human Use, Lab Use Only.

MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM.
    MMV-667492 exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787.
    MMV-667492 is a novel antimetastatic agent for the treatment of metastatic osteosarcoma.

    Physicochemical Properties

    M.Wt 313.357
    Formula C17H19N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-(cyclohexylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-methylnitrous amide

    References

    1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507.

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