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Chemical Structure : NSC-5844
CAS No.: 140926-75-6
Catalog No.: PC-42044Not For Human Use, Lab Use Only.
A bis-quinoline with diverse biological activities, inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine with IC50 of 17 and 27 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $280 | In stock | |
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock |
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A bis-quinoline with diverse biological activities, inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine with IC50 of 17 and 27 nM, respectively; also inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.8 uM; also inhibits the metalloprotease activity of BoNT serotype A light chain (BoNT/A LC).
| M.Wt | 383.2738 | |
| Formula | C20H16Cl2N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)- |
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1. Vennerstrom JL, et al. J Med Chem. 1992 May 29;35(11):2129-34.
2. Zhang H, et al. Biomed Pharmacother. 2008 Feb;62(2):65-9.
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