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Chemical Structure : NU-6300
CAS No.: 2070015-09-5
Catalog No.: PC-45559Not For Human Use, Lab Use Only.
NU-6300 is the first covalent, irreversible, ATP-Competitive CDK2 inhibitor with Ki of 6 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 25 mg | $598 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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NU-6300 is the first covalent, irreversible, ATP-Competitive CDK2 inhibitor with Ki of 6 nM.
NU-6300 shows modest effect (GI50=8 uM) against human MCF-7 breast carcinoma cells.
NU-6300 inhibits Rb phosphorylation in Rb-positive SKUT-1B cells.
| M.Wt | 413.4933 | |
| Formula | C20H23N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine |
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1. Anscombe E, et al. Chem Biol. 2015 Sep 17;22(9):1159-64.
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