Catalog No.: PC-45950Not For Human Use, Lab Use Only.
NVP-BKM120 (BKM-120, Buparlisib) is a potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
NVP-BKM120 (BKM-120, Buparlisib) is a potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
NVP-BKM120 (BKM-120, Buparlisib) much less effectively inhibits the class III PI3K Vps34 and mTOR, and has no effect on PI4Kβ and several other kinases.
NVP-BKM120 (BKM-120, Buparlisib) prevents the growth of assorted cancer cell lines when used at 5 μM and inhibits tumor growth in vivo.
