Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Cannabinoid Receptor-Otenabant
Otenabant

Chemical Structure : Otenabant

CAS No.: 686344-29-6

Otenabant (CP 945598;CP-945598;CP945598)

Catalog No.: PC-42723Not For Human Use, Lab Use Only.

Otenabant (CP-945598) is a potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.

Packing Price Stock Quantity
10 mg $88 In stock
25 mg $138 In stock
50 mg $218 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Otenabant (CP-945598) is a potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.
Otenabant (CP-945598) has low affinity (Ki=7600 nM) for human CB2 receptors.
Otenabant (CP-945598) reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.

Physicochemical Properties

M.Wt 510.4183
Formula C25H25Cl2N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-

References

1. Fulp A, et al. J Med Chem. 2012 Nov 26;55(22):10022-32.

2. Hadcock JR, et al. Biochem Biophys Res Commun. 2010 Apr 2;394(2):366-71.

3. Aronne LJ, et al. Obesity (Silver Spring). 2011 Jul;19(7):1404-14.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: