Chemical Structure : PARP inhibitor PJ-34
CAS No.:
344458-19-1
PARP inhibitor PJ-34
(PJ34)
Catalog No. : PC-21820Not For Human Use, Lab Use Only.
PJ34 is a potent specific inhibitor of PARP1/2 with IC50 of 110 nM and 86 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2182001
Biological Activity
PJ34 is a potent specific inhibitor of PARP1/2 with IC50 of 110 nM and 86 nM, respectively.
Physicochemical Properties
M.Wt
295.34
Formula
C17H17N3O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide
References
1. Haddad M, et al. Br J Pharmacol. 2006 Sep;149(1):23-30.
2. Abdelkarim GE, et al. Int J Mol Med. 2001 Mar;7(3):255-60.
3. Iványi Z, et al. Shock. 2003 May;19(5):415-21.
4. Pacher P, et al. J Pharmacol Exp Ther. 2002 Mar;300(3):862-7.
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