Chemical Structure : PD0325901
CAS No.:
391210-10-9
PD0325901
(Mirdametinib, PD325901, PD-0325901)
Catalog No. : PC-42489Not For Human Use, Lab Use Only.
Mirdametinib (PD0325901) is a selective, non ATP-competitive MEK inhibitor with IC50 of 0.33 nM.
Packing Price Stock Quantity 10 mg $78 In stock 0 1 2 3 4 5 25 mg $128 In stock 0 1 2 3 4 5 50 mg $198 In stock 0 1 2 3 4 5 100 mg $328 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4248901
Biological Activity
Mirdametinib (PD0325901) is a selective, non ATP-competitive MEK inhibitor with IC50 of 0.33 nM.
Physicochemical Properties
M.Wt
482.1931
Formula
C16H14F3IN2O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 56 mg/mL
Chemical Name/SMILES
Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
References
1. Barrett SD, et al. Bioorg Med Chem Lett.
2. Ciuffreda L, et al. Neoplasia.
3. Henderson YC, et al. Mol Cancer Ther.
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