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Chemical Structure : PF-04971729
CAS No.: 1210344-57-2
Catalog No.: PC-44436Not For Human Use, Lab Use Only.
Ertugliflozin (PF-04971729) is a potent and selective SGLT2 inhibitor with IC50 of 0.877 nM for hSGLT2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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Ertugliflozin (PF-04971729) is a potent and selective SGLT2 inhibitor with IC50 of 0.877 nM for hSGLT2.
Ertugliflozin shows >2000-fold selectivity over hSGLT1.
Ertugliflozin demonstrates robust urinary glucose excretion in rats and an excellent preclinical safety profile.
| M.Wt | 436.8827 | |
| Formula | C22H25ClO7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 46 mg/mL |
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| Chemical Name/SMILES |
β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- |
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1. Mascitti V, et al. J Med Chem. 2011 Apr 28;54(8):2952-60.
2. Kalgutkar AS, et al. Drug Metab Dispos. 2011 Sep;39(9):1609-19.
3. Miao Z, et al. Drug Metab Dispos. 2013 Feb;41(2):445-56.
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