Chemical Structure : PF670462
CAS No.: 950980-98-0
Catalog No.: PC-49496Not For Human Use, Lab Use Only.
PF-670462 (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively, causes a significant phase delay in animal models of circadian rhythm.
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PF-670462 (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively, causes a significant phase delay in animal models of circadian rhythm.
M.Wt | 337.40 | |
Formula | C19H20FN5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-[3-cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyrimidin-2-ylamine |
1. Badura L, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):730-8.
2. Bryant CD, et al. Psychopharmacology (Berl). 2009 May;203(4):703-11.
3. Walton KM, et al. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9.
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