PRT-4165 |CAS:31083-55-3 Probechem Biochemicals

Chemical Structure : PRT-4165

CAS No.: 31083-55-3

PRT-4165 (NSC-600157)

Catalog No.: PC-45731Not For Human Use, Lab Use Only.

PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.

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25 mg	$258	In stock
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Biological Activity

PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
PRT-4165 inhibits double-strand breaks (DSBs) repair.

Physicochemical Properties

M.Wt	235.2375
Formula	C15H9NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-

References

1. Ismail IH, et al. J Biol Chem. 2013 Sep 13;288(37):26944-54.

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PRT-4165 (NSC-600157)

Biological Activity

Physicochemical Properties

References

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