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Chemical Structure : Pagoclone
CAS No.: 133737-32-3
Catalog No.: PC-42414Not For Human Use, Lab Use Only.
A potent, orally active GABAA receptor agonist with high affinity (0.7-9.1nM) to the benzodiazepine binding site of GABAA receptors containing either an α1, α2, α3 or α5 subunit.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $224 | In stock |
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A potent, orally active GABAA receptor agonist with high affinity (0.7-9.1nM) to the benzodiazepine binding site of GABAA receptors containing either an α1, α2, α3 or α5 subunit; exhibits significant anxiolytic-like activity in vivo.
Anxiety
Phase 3 Discontinued
| M.Wt | 407.89268 | |
| Formula | C23H22ClN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Isoindol-1-one, 2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-, (+)- |
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1. Atack JR. Expert Opin Investig Drugs. 2005 May;14(5):601-18.
2. Atack JR, et al. Neuropharmacology. 2006 May;50(6):677-89.
3. Caveney AF, et al. Neuropsychiatr Dis Treat. 2008 Feb;4(1):277-82.
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