Catalog No.: PC-24833Not For Human Use, Lab Use Only.
Pinosylvin is a naturally occurring molecule traditionally found in pinus trees with antibacterial, antifungal and anticancer activity, shows potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae.
Pinosylvin is a naturally occurring molecule traditionally found in pinus trees with antibacterial, antifungal and anticancer activity, shows potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae. Pinosylvin selectively inhibits LPS- and RANKL-induced release of IL-1beta effectively reducing osteoclastogenesis. Pinosylvin significantly inhibits the release of pro-inflammatory cytokines (TNF-α and IL-6) and NO mediator in LPS-stimulated RAW 264.7 cells. Pinosylvin showed its anti-inflammatory activity by inhibiting the PGE2 production mediated by COX-2 in RAW 264.7 cells treated with LPS (1 µg/mL) with an IC50 value of 10.6 µM. Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial-mesenchymal transition and inhibition of MMP-2.
Physicochemical Properties
M.Wt
212.25
Formula
C14H12O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
trans-3,5-dihydroxystilbene
References
1. Perri MR, et al. Pharmaceuticals (Basel). 2023 May 9;16(5):718.
2. Zhang W, et al. Adv Sci (Weinh). 2025 Jun 10:e01532.
