Sobetirome (QRX-431) | TRβ1 agonist | Probechem Biochemicals

Chemical Structure : QRX-431

CAS No.: 211110-63-3

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431)

Catalog No.: PC-20362Not For Human Use, Lab Use Only.

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
50 mg	$428	In stock
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Biological Activity

QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively.

Physicochemical Properties

M.Wt	328.41
Formula	C20H24O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid

References

1. Trost SU, et al. Endocrinology. 2000 Sep;141(9):3057-64.

2. Ribeiro MO, et al. J Clin Invest. 2001 Jul;108(1):97-105.

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QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431)

Biological Activity

Physicochemical Properties

References

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