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Chemical Structure : RO-8994
CAS No.: 1309684-94-3
Catalog No.: PC-45124Not For Human Use, Lab Use Only.
A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
Bulk size, bulk discount!
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A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM; shows marked improvement in both in vitro and in vivo pharmacological properties.
| M.Wt | 613.5067 | |
| Formula | C31H31Cl2FN4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 45 mg/mL |
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| Chemical Name/SMILES |
Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R)- |
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1. Zhang Z, et al. Bioorg Med Chem. 2014 Aug 1;22(15):4001-9.
2. Yu B, et al. Anticancer Agents Med Chem. 2016;16(10):1315-24.
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