Catalog No.: PC-42530Not For Human Use, Lab Use Only.
Regorafenib (BAY 73-4506) is a potent multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM).
Regorafenib (BAY 73-4506) is a potent multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM).
Regorafenib (BAY 73-4506) inhibits VEGFR1/2/3, PDGFRβ, FGFR1, KIT, RET and B-RAF etc.
Regorafenib (BAY 73-4506) exhibits potent dose-dependent TGI in various preclinical human xenograft models in mice; orally active.
