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Chemical Structure : Retro 2
CAS No.: 1201652-50-7
Catalog No.: PC-62658Not For Human Use, Lab Use Only.
Retro 2 (Retro-2) is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
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|---|---|---|---|
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| 10 mg | $238 | In stock | |
| 25 mg | $428 | In stock | |
| 50 mg | $728 | In stock | |
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Retro 2 (Retro-2) is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
Retro 2 has no effect on endogenous retrograde cargo proteins.
Retro 2 protects mice against ricin challenge.
| M.Wt | 320.41 | |
| Formula | C19H16N2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(E)-2-(((5-methylthiophen-2-yl)methylene)amino)-N-phenylbenzamide |
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1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42.
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