Chemical Structure : SBFI-26
CAS No.: 1541209-75-9
Catalog No.: PC-61177Not For Human Use, Lab Use Only.
SBFI-26 (SBFI26) is a small molecule inhibitor of epidermal- and brain-specific FABP5 and FABP7 that effectively increases anandamide signaling.
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SBFI-26 (SBFI26) is a small molecule inhibitor of epidermal- and brain-specific FABP5 and FABP7 that effectively increases anandamide signaling.
SBFI-26 dose-dependently reduces mechanical hyperalgesia in vivo, demonstrates significant analgesic and anti-inflammatory properties.
SBFI-26 also suppresses the malignant progression of castration resistant prostate cancer cells by competitively binding to oncogenic FABP5.
M.Wt | 422.48 | |
Formula | C28H22O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2,4-Diphenylcyclobutane-1,3-dicarboxylic acid mono-1-naphthyl ester |
1. Peng X, et al. Mol Pain. 2017 Jan;13:1744806917697007.
2. Hsu HC, et al. Biochemistry. 2017 Jul 11;56(27):3454-3462.
3. Al-Jameel W, et al. Oncotarget. 2017 May 9;8(19):31041-31056.
4. Thanos PK, et al. Front Psychiatry. 2016 Apr 5;7:54.
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