Catalog No.: PC-20417Not For Human Use, Lab Use Only.
SLU-PP-1072 is a potent, selective, dual ERRα/γ inverse agonist, inhibits ERRα- and ERRγ-dependent transcription in cotransfection assays with IC50 of 4.8 and 0.9 uM.
SLU-PP-1072 is a potent, selective, dual ERRα/γ inverse agonist, inhibits ERRα- and ERRγ-dependent transcription in cotransfection assays with IC50 of 4.8 and 0.9 uM.
SLU-PP-1072 does not inhibit ERRβ, does not display estrogen receptor activity.
SLU-PP-1072 alters PCa cell metabolism and gene expression, resulting in cell cycle dysregulation and increased apoptosis without acute mitochondrial uncoupling activity.
SLU-PP-1072 is a unique chemical tool to evaluate the pharmacology of ERRα and ERRγ.
