Sirt2-PROTAC-1 |CAS:2098487-75-1 Probechem Biochemicals

Chemical Structure : Sirt2-PROTAC-1

Catalog No.: PC-60096Not For Human Use, Lab Use Only.

A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM)..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).

M.Wt	852.942
Formula	C40H40N10O8S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

1. Schiedel M, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01872.