Chemical Structure : TCA-1
Catalog No.: PC-70348Not For Human Use, Lab Use Only.
A small molecule with activity against drug-resistant and persistent tuberculosis.
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A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models; down-regulates genes known to be involved in Mtb persistence; inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis.
M.Wt | 375.417 | |
Formula | C16H13N3O4S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Wang F, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7.
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