Catalog No.: PC-70298Not For Human Use, Lab Use Only.
UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
UVI-3003 does not affect the corepressor interaction capacity of the RARα subunit in the RAR-RXR heterodimer configuration.
