Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : UVI-3003
CAS No.: 847239-17-2
Catalog No.: PC-70298Not For Human Use, Lab Use Only.
UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
UVI-3003 does not affect the corepressor interaction capacity of the RARα subunit in the RAR-RXR heterodimer configuration.
| M.Wt | 436.6 | |
| Formula | C28H36O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid |
|
1. Habchi J, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208.
2. Nahoum V, et al. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
