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Chemical Structure : WS-3
CAS No.: 1421227-52-2
Catalog No.: PC-43044Not For Human Use, Lab Use Only.
WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $158 | In stock | |
| 50 mg | $268 | In stock | |
| 100 mg | $458 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM, modulates the activity of Erb3 binding protein-1 and the IκB kinase pathway.
WS3 can reversibly proliferates primary RPE cells isolated from fetal and adult human donors.
| M.Wt | 569.5781 | |
| Formula | C28H30F3N7O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 43 mg/mL |
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| Chemical Name/SMILES |
Cyclopropanecarboxamide, N-[6-[4-[[[[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-4-pyrimidinyl]- |
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1. Swoboda JG, et al. ACS Chem Biol. 2013 Jul 19;8(7):1407-11.
2. Shen W, et al. J Am Chem Soc. 2013 Feb 6; 135(5):1669-72.
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