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Zoldonrasib

Chemical Structure : Zoldonrasib

CAS No.: 3034802-05-3

Zoldonrasib

Catalog No.: PC-24200Not For Human Use, Lab Use Only.

Zoldonrasib is a potent, selective peptide-linked macrocyclic dipeptidic inhibitor of KRas.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Zoldonrasib is a potent, selective peptide-linked macrocyclic dipeptidic inhibitor of KRas.

Physicochemical Properties

M.Wt 1168.46
Formula C63H88F3N11O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C1OCC(C)(CC2=C(C3=CC(N4CCN(C5CC5)CC4)=CN=C3[C@H](C)OC)N(CC(F)(F)F)C6=CC=C(N7CCO[C@@H](C[C@H](C(N8N[C@H]1CCC8)=O)NC([C@H](C9CCCC9)N%10CC[C@@]%11(C%10)CN(CC%11)C([C@@H]%12N([C@@H]%12C%13CC%13)C)=O)=O)C7)C=C26)C

References

1. Patent WO2023060253 A1.

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