Catalog No.: PC-43029Not For Human Use, Lab Use Only.
Zotarolimus (ABT-578, A 179578) is a semi-synthetic analogue of rapamycin, inhibits FKBP-12 binding with IC50 of 2.8 nM and shows less potent systemic immunosuppression than rapamycin.
Zotarolimus (ABT-578, A 179578) is a semi-synthetic analogue of rapamycin, inhibits FKBP-12 binding with IC50 of 2.8 nM and shows less potent systemic immunosuppression than rapamycin.
Zotarolimus (ABT-578, A 179578) effectively inhibits both smooth muscle cell and endothelial cell proliferation, with IC50 values of 2.9 nM and 2.6 nM, respectively.
Zotarolimus (ABT-578, A 179578) exhibits high-affinity binding to the immunophilin FKBP12, inhibiting in vitro proliferation of both human and rat T cells.
Zotarolimus (ABT-578, A 179578) inhibits Con A-induced human T cells with IC50 of 7.0 nM.
Zotarolimus (ABT-578, A 179578) reduces early complications and improve late clinical outcomes in patients needing interventional cardiology.
