hSMG-1 inhibitor 11e |CAS:1402452-10-1 Probechem Biochemicals

Chemical Structure : hSMG-1 inhibitor 11e

CAS No.: 1402452-10-1

hSMG-1 inhibitor 11e (hSMG-1-IN-11e)

Catalog No.: PC-35788Not For Human Use, Lab Use Only.

hSMG-1 inhibitor 11e is a potent, selective PI3K-related protein kinase hSMG-1 inhibitor with IC50 of <0.05 nM, >900-fold selectivity over mTOR, and no significant activity against CDK1/2.

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2 mg	$198	In stock
5 mg	$328	In stock
10 mg	$528	In stock
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Biological Activity

hSMG-1 inhibitor 11e is a potent, selective PI3K-related protein kinase hSMG-1 inhibitor with IC50 of <0.05 nM, >900-fold selectivity over mTOR, and no significant activity against CDK1/2.

Physicochemical Properties

M.Wt	517.608
Formula	C26H27N7O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N,2-trimethyl-5-((4-(2-(4-(3-methylureido)phenyl)pyridin-4-yl)pyrimidin-2-yl)amino)benzenesulfonamide

References

1. Gopalsamy A, et al. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6636-41.

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hSMG-1 inhibitor 11e (hSMG-1-IN-11e)

Biological Activity

Physicochemical Properties

References

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