kb-NB142-70 |CAS:1233533-04-4 Probechem Biochemicals

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Chemical Structure : kb-NB142-70

CAS No.: 1233533-04-4

kb-NB142-70 (kb NB 142-70)

Catalog No.: PC-63036Not For Human Use, Lab Use Only.

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.

Packing	Price	Stock
10 mg	$128	In stock
25 mg	$198	In stock
50 mg	$328	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.
kb NB142 70 displays 10-fold increase in the in vitro PKD1 inhibitory potency versus CID755673.
kb NB142 70 inhibits PC-3, PANC-1, CFPAC-1 cellular growth with IC50 of 5-30 uM.

Physicochemical Properties

M.Wt	251.318
Formula	C11H9NO2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one

References

1. Bravo-Altamirano K, et al. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

2. Guo J, et al. Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.

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kb-NB142-70 (kb NB 142-70)

Biological Activity

Physicochemical Properties

References

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