Chemical Structure : kb-NB142-70
CAS No.: 1233533-04-4
Catalog No.: PC-63036Not For Human Use, Lab Use Only.
kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.
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kb NB142-70 is a potent and selective PKD inhibitor with IC50 of 28.3 nM.
kb NB142 70 displays 10-fold increase in the in vitro PKD1 inhibitory potency versus CID755673.
kb NB142 70 inhibits PC-3, PANC-1, CFPAC-1 cellular growth with IC50 of 5-30 uM.
M.Wt | 251.318 | |
Formula | C11H9NO2S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one |
1. Bravo-Altamirano K, et al. ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.
2. Guo J, et al. Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.
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