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Chemical Structure : o-vanillin
CAS No.: 148-53-8
Catalog No.: PC-62974Not For Human Use, Lab Use Only.
o-vanillin (C29L, ortho-Vanillin) is the C29 derivative that blocks hTLR2/1 and hTLR2/6 signaling with IC50 of 24.2 uM and 37.2 uM in NF-κB reporter assay in HEK293T cells, respectively.
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o-vanillin (C29L, ortho-Vanillin) is the C29 derivative that blocks hTLR2/1 and hTLR2/6 signaling with IC50 of 24.2 uM and 37.2 uM in NF-κB reporter assay in HEK293T cells, respectively.
o-vanillin (C29L, ortho-Vanillin) significantly blocks IL-12 p40 and TNF-α liver cytokine mRNA and serum protein, inhibits TLR2/1-induced proinflammatory cytokines in mice.
o-vanillin (C29L, ortho-Vanillin) is more soluble in water than C29.
| M.Wt | 152.15 | |
| Formula | C8H8O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Hydroxy-3-methoxybenzaldehyde |
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1. Mistry P, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5455-60.
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