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Cat. No. Product Name Information
PC-43467

Nepicastat hydrochloride

Dopamine beta-hydroxylase inhibitor

Nepicastat (RS-25560-197, SYN117) hydrochloride is a potent, selective, orally active inhibitor of dopamine-beta-hydroxylase (DBH) with IC50 of 8.5 and 9.0 nM for bovine and human DBH, respectively.
PC-43466

Nepicastat

Dopamine beta-hydroxylase inhibitor

Nepicastat (RS-25560-197, SYN-117) is a potent, selective, orally active inhibitor of dopamine-beta-hydroxylase (DBH) with IC50 of 8.5 and 9.0 nM for bovine and human DBH, respectively.
PC-22597

Etamicastat hydrochloride

Dopamine beta-hydroxylase inhibitor

Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent, peripherally selective and reversible dopamine-β-hydroxylase (DβH) inhibitor with IC50 of 107 nM, reduces the biosynthesis of norepinephrine (noradrenaline).
PC-22596

Zamicastat

Dopamine beta-hydroxylase inhibitor

Zamicastat (BIA 5-1058) is a potent, selective dopamine β-hydroxylase (DβH) inhibitor, decreases noradrenaline and increases dopamine levels.

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