| Cat. No. |
Product Name |
Information |
| PC-20176 |
RXC004
Porcupine inhibitor
|
RXC004 (RXC-004, Zamaporvint) is a potent, selective Porcupine (PRCN) inhibitor, inhibits functional Wnt production from mouse L-Wnt3a cells with IC50 of 64 pM in luciferase reporters assays. |
| PC-20098 |
WHN-88
Porcupine inhibitor
|
WHN-88 is a potent, selective Porcupine (PORCN) inhibitor, inhibits Wnt/β-catenin signaling with IC50 of ST-Luc of 0.02 uM. |
| PC-49489 |
IWP-L6
Porcupine inhibitor
|
IWP-L6 is a potent, selective inhibitor of Porcupine with EC50 of 0.5 nM. |
| PC-49488 |
GNF-1331
Porcupine inhibitor
|
GNF-1331 is a potent, selective inhibitor of Porcupine, binds to PORCN in a radioligand binding assay with IC50 of 8 nM. |
| PC-72828 |
ECT-159
Porcupine inhibitor
|
ECT-159 (ETC-1922159) is a potent, orally available Porcupine (PORCN) inhibitor that blocks the secretion and activity of all Wnts, inhibits β-catenin reporter activity with IC50 of 2.9 nM. |
| PC-38141 |
CGX1321
Porcupine inhibitor
|
CGX1321 (CGX-1321) is a nove potent and specific inhibitor of porcupine (PORCN) that inhibits Wnt pathway, block secretion of WNT proteins with IC50 of 1 nM. |
| PC-62803 |
IWP-O1
Porcupine inhibitor
|
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor with EC50 of 80 pM in L-Wnt-STF cells, effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. |
| PC-42139 |
GNF-6231
Porcupine inhibitor
|
GNF-6231 (GNF6231) is a potent, selective and orally bioavailable Porcupine (PORCN) inhibitor with IC50 of 0.8 nM. |
| PC-45342 |
LGK974
Porcupine inhibitor
|
LGK974 (WNT974) is a potent and specific small-molecule Porcupine (PORCN) inhibitor with IC50 of 1 nM in the PORCN radioligand binding assay. |
