Cat. No. |
Product Name |
Information |
PC-35231 |
GC376
3CLpro inhibitor
|
GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays. |
PC-63579 |
IMP-1088
N-myristoyltransferase inhibitor
|
IMP-1088 is a potent, selective human N-myristoyltransferase with IC50 of less than 1 nM for both HsNMT1 and HsNMT2, inhibits Rhinoviruses (RVs) capsid myristoylation in cells. |
PC-63345 |
Rupintrivir
Rhinovirus 3C protease inhibitor
|
Rupintrivir (AG-7088, AG7088) is a potent, irreversible inhibitor of human rhinovirus 3C protease, inhibits the replication of all HRV serotypes with EC50 of 23 nM and EC90 of 82 nM. |
PC-45760 |
Pleconaril
|
Pleconaril (Picovir, VP-63843, Win-63843) is a broad spectrum antipicornaviral agent that inhibits rhinovirus replication by interaction with the VP1 protein. |
PC-21961 |
AZ5385
Rhinovirus inhibitor
|
AZ5385 is a small molecule EGFR inhibitor, also exhibits potent anti-HRV (human rhinovirus) activity with EC50 of 0.35 uM for HRV-2 in cell protection colorimetric assay, targeting the VP1 pocket of HRV. |
PC-21696 |
OBR-5-340
Viral capsid inhibitor
|
OBR-5-340 is a potent, orally bioavailable inhibitor targeting capsid of Rhino- and Enteroviruses,exhibits broad-spectrum antiviral activity against of enteroviruses and rhinoviruses. |
PC-70357 |
WIN 52084
|
An antiviral compound that inhibits attachment to cells, inhibits human rhinovirus type 14 (HRV14) replication.. |
PC-70356 |
Disoxaril
|
A picornavirus replication inhibitor by binding to the hydrophobic pocket within the VP1 coat protein, thus stabilizing the virion and blocking its uncoating.. |