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Chemical Structure : 3M-002
CAS No.: 256922-53-9
Catalog No.: PC-70302Not For Human Use, Lab Use Only.
3M-002 (CL-075) is a selective TLR8 agonist that induces activation of NF-κB at 0.4 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $158 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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3M-002 (CL-075) is a selective TLR8 agonist that induces activation of NF-κB at 0.4 uM.
3M-002 (CL-075) induces similar cytokine profiles from human PBMC compared with TLR8 agonist ssRNA.
3M-002 (CL-075) effectively stimulates IL-12 production from mDC, but not pDC.
3M-002 (CL-075) induces TNF-α and IL-12 at 0.1 uM from monocytes and monocyte-derived DC (Mo-DC).
| M.Wt | 243.33 | |
| Formula | C13H13N3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-propylthiazolo[4,5-c]quinolin-4-amine |
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1. Gorden KB, et al. J Immunol. 2005 Feb 1;174(3):1259-68.
2. Spranger S, et al. J Immunol. 2010 Jul 1;185(1):738-47.
3. Makni-Maalej K, et al. J Leukoc Biol. 2015 Jun;97(6):1081-7.
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