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Chemical Structure : A-17
Catalog No.: PC-70363Not For Human Use, Lab Use Only.
A potent Hsp90α/p23 interaction inhibitor with IC50 of 0.15 uM, more effective than CP-9 in degrading pAkt/total Akt and Raf-1.
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A potent Hsp90α/p23 interaction inhibitor with IC50 of 0.15 uM, more effective than CP-9 in degrading pAkt/total Akt and Raf-1; inhibits Hsp90(α/β)/p23 interactions and degrading Hsp90 client proteins in cell culture, but not in live mice.
| M.Wt | 384.333 | |
| Formula | C15H11F3N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chan CT, et al. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2476-85.
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