AK-3280 | Antifibrotic agent | Probechem Biochemicals

Chemical Structure : AK-3280

AK-3280 (AK 3280, GDC3280, RG 6069)

Catalog No.: PC-72631Not For Human Use, Lab Use Only.

AK-3280 (AK 3280, GDC 3280, RG 6069) is an orally available, potential novel anti-fibrotic small molecule under investigation for the treatment of interstitial lung diseases.

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Biological Activity

AK-3280 (AK 3280, GDC 3280, RG 6069) is an orally available, potential novel anti-fibrotic small molecule under investigation for the treatment of interstitial lung diseases.

Physicochemical Properties

M.Wt	388.35
Formula	C19H15F3N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-methyl-7-(1-methyl-1H-pyrazol-4-yl)-5-(4-(trifluoromethoxy)phenyl)-1,5-dihydro-4H-benzo[d]imidazol-4-one

References

1. Cheung D, et al. Pulm Pharmacol Ther. 2021 Aug;69:102051.

2. Wang J, et al. Biomed Chromatogr. 2019 Apr;33(4):e4482.

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AK-3280 (AK 3280, GDC3280, RG 6069)

Biological Activity

Physicochemical Properties

References

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