Chemical Structure : AZ-3451
CAS No.: 2100284-59-9
Catalog No.: PC-60321Not For Human Use, Lab Use Only.
AZ-3451 (AZ 3451, AZ3451) is a potent, and selective PAR2 antagonist with Kd of 13.5 nM.
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AZ-3451 (AZ 3451, AZ3451) is a potent, and selective PAR2 antagonist with Kd of 13.5 nM; shows excellent selectivity over PAR1 and PAR4 (>50 uM).
M.Wt | 571.475 | |
Formula | C30H27BrN4O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-2-(6-bromobenzo[d][1,3]dioxol-5-yl)-N-(4-cyanophenyl)-1-(1-cyclohexylethyl)-1H-benzo[d]imidazole-5-carboxamide |
1. Cheng RKY, et al. Nature. 2017 May 4;545(7652):112-115.
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