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Chemical Structure : BIBR-1532
CAS No.: 321674-73-1
Catalog No.: PC-45170Not For Human Use, Lab Use Only.
BIBR-1532 is a potent and selective telomerase inhibitor with IC50 of 5 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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BIBR-1532 is a potent and selective telomerase inhibitor with IC50 of 5 uM.
BIBR-1532 shows selective cytotoxicity and telomere damage in leukemia cells with IC50 of 30-80 uM.
BIBR-1532 also sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment.
| M.Wt | 331.3646 | |
| Formula | C21H17NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzoic acid, 2-[[(2E)-3-(2-naphthalenyl)-1-oxo-2-buten-1-yl]amino]- |
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1. Barma DK, et al. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1333-6.
2. Pascolo E, et al. J Biol Chem. 2002 May 3;277(18):15566-72.
3. Ward RJ, et al. Mol Pharmacol. 2005 Sep;68(3):779-86.
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