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Chemical Structure : Bisperoxovanadium
Catalog No.: PC-62443Not For Human Use, Lab Use Only.
Bisperoxovanadium (bpV(phen) potassium hydrate) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=343 nM), and PTP-1β (IC50=920 nM).
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Bisperoxovanadium (bpV(phen) potassium hydrate) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=343 nM), and PTP-1β (IC50=920 nM).
Bisperoxovanadium activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase.
| M.Wt | 404.3 | |
| Formula | C12H8N2O5V • K+(H2O)3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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