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Chemical Structure : CASK inhibitor 18
Catalog No.: PC-72703Not For Human Use, Lab Use Only.
CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM.
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CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM.
CASK (Ca2+/calmodulin-dependent Ser/Thr kinase) is a member of the MAGUK (membrane-associated guanylate kinase) family that functions as neurexin kinases with roles implicated in neuronal synapses and trafficking.
CASK chemical probe 18 is a first chemical probe for studying the biological roles of CASK.
| M.Wt | 610.351 | |
| Formula | C24H30Br2N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nadine Russ, et al. J Med Chem. 2021 Oct 14;64(19):14358-14376.
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