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Chemical Structure : DX-600
CAS No.: 478188-26-0
Catalog No.: PC-38238Not For Human Use, Lab Use Only.
DX-600 (DX600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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DX-600 (DX600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM.
DX-600 exhibits non-competitive type of inhibition and not inhibit ACE activity.
DX-600 is a useful tool compound in elucidation of ACE2 in vivo function, as well as the recent SARS CoV-2 viral entry via huamn ACE2.
| M.Wt | 3188.37 | |
| Formula | C141H185N35O40S2.C2HF3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in H2O (31.8 mg/mL) |
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| Chemical Name/SMILES |
Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2 trifluoroacetate salt (Disulfide bond) |
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1. Huang L, et al. J Biol Chem. 2003 May 2;278(18):15532-40.
2. Li N, et al. Am J Physiol Renal Physiol. 2005 Feb;288(2):F353-62.
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