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Chemical Structure : ENPP1 inhibitor 32
CAS No.: 2298391-60-1
Catalog No.: PC-38280Not For Human Use, Lab Use Only.
ENPP1 inhibitor 32 is a potent, cell-impermeable small molecule inhibitor of ENPP1 with Ki of < 2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $198 | In stock | |
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ENPP1 inhibitor 32 is a potent, cell-impermeable small molecule inhibitor of ENPP1 with Ki of < 2 nM,
ENPP1 inhibitor 32 prevents cGAMP degradation in mouse and human plasma at nanomolar concentrations (IC95=40 nM).
ENPP1 inhibitor 32 exhibits excellent physicochemical and pharmacokinetic properties, and delays tumor growth in a breast cancer mouse model.
| M.Wt | 351.343 | |
| Formula | C16H22N3O4P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO (3.5 mg/mL) |
|
| Chemical Name/SMILES |
P-[2-[1-(8-Methoxy-4-quinazolinyl)-4-piperidinyl]ethyl]phosphonic acid |
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1. Jacqueline A Carozza, et al. Cell Chem Biol. 2020 Nov 19;27(11):1347-1358.e5.
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