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EOS-984

Chemical Structure : EOS-984

CAS No.: 2724937-55-5

EOS-984 (EOS984)

Catalog No.: PC-23833Not For Human Use, Lab Use Only.

EOS-984 is a first-in-class, potent and highly selective inhibitor of equilibrative nucleoside transporter 1 (ENT1), inhibits the immunosuppressive activity of adenosine and restore immune cell proliferation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

EOS-984 is a first-in-class, potent and highly selective inhibitor of equilibrative nucleoside transporter 1 (ENT1), inhibits the immunosuppressive activity of adenosine and restore immune cell proliferation.

Physicochemical Properties

M.Wt 629.75
Formula C33H47N3O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O(C)C=1C2=CC(=CC1OC)C(=O)NCCCN3CCN(CC[C@H](OC(=O)C4=CC(OC)=C(OC)C(OC)=C4)CCCO2)CCC3

References

1. Patent WO2021204896 A1.

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