Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GW-766994 R-form
Catalog No.: PC-35230Not For Human Use, Lab Use Only.
GW-766994 (GW766994) is a potent, selective, orally available CCR3 antagonist with pKi of 7.86 for inhibiting eotaxin-induced eosinophil chemotaxis in vitro assays.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GW-766994 (GW766994) is a potent, selective, orally available CCR3 antagonist with pKi of 7.86 for inhibiting eotaxin-induced eosinophil chemotaxis in vitro assays; reverses CCL11-induced activation of CDK5 at 10 uM in rat neurons expressed CCR3, blocks CCL11-induced the production of Aβ and dendritic spine loss in the hippocampal neuronal cultures.
| M.Wt | 451.348 | |
| Formula | C21H24Cl2N4O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Neighbour H, et al. Clin Exp Allergy. 2014 Apr;44(4):508-16.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
