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INH-6

Chemical Structure : INH-6

CAS No.: 1001753-24-7

INH-6 (INH6)

Catalog No.: PC-42194Not For Human Use, Lab Use Only.

INH-6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.

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Biological Activity

INH-6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
INH-6 triggers mitotic abnormalities and induces apoptosis.

Physicochemical Properties

M.Wt 322.424
Formula C19H18N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-

References

1. Qiu XL, et al. J Med Chem. 2009 Mar 26;52(6):1757-67.

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