KP-1339 |CAS:197723-00-5 Probechem Biochemicals

Chemical Structure : KP-1339

KP-1339 (IT-139;NKP-1339)

Catalog No.: PC-60227Not For Human Use, Lab Use Only.

A promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent.

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Biological Activity

A promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent; potentiates the anticancer activity of sorafenib in vitro and in vivo; overcomes GRP78-mediated chemoresistance, restores sensitivity to cytotoxic drugs in drug-resistant PDAC cells in vitro and in vivo.

Physicochemical Properties

M.Wt	502.138
Formula	C14H12Cl4N4NaRu
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES

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KP-1339 (IT-139;NKP-1339)

Biological Activity

Physicochemical Properties

References

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