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Chemical Structure : LY-2955303
CAS No.: 1433497-19-8
Catalog No.: PC-62836Not For Human Use, Lab Use Only.
LY-2955303 is a potent and selective RARγ antagonist with binding Ki of 1.09 nM, displays >1000-fold selectivity against RARα and RARβ.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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LY-2955303 is a potent and selective RARγ antagonist with binding Ki of 1.09 nM, displays >1000-fold selectivity against RARα and RARβ.
LY-2955303 demonstrates good pharmacokinetic properties and efficacious in the MIA model of osteoarthritis-like joint pain.
| M.Wt | 578.76 | |
| Formula | C36H42N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-[5-[3,5-Bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]benzoic acid |
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1. Hughes NE, et al. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3274-7.
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