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Chemical Structure : ML-241 hydrochloride
CAS No.:
Catalog No.: PC-45719Not For Human Use, Lab Use Only.
ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $104 | In stock | |
| 25 mg | $232 | In stock | |
| 50 mg | $400 | In stock | |
| 100 mg | $680 | In stock |
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ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.
| M.Wt | 408.9238 | |
| Formula | C23H25ClN4O | |
| CAS No. | ||
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name |
4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-,hydrochloride |
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1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.
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