Necrocide-1 | Necrosis inducer | Probechem Biochemicals

Chemical Structure : Necrocide-1

Necrocide-1 (Necrocide 1, NC1)

Catalog No.: PC-23519Not For Human Use, Lab Use Only.

Necrocide-1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively

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Biological Activity

Necrocide-1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively

Physicochemical Properties

M.Wt	365.47
Formula	C23H27NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-Indol-2-one, 3-cycloheptyl-1,3-dihydro-3-(4-hydroxyphenyl)-6-Methoxy-7-Methyl-, (3S)-

References

1. Jing Zhang, et al. Cell Death Dis. 2023 Apr 5;14(4):238.

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Necrocide-1 (Necrocide 1, NC1)

Biological Activity

Physicochemical Properties

References

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