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PK-14105

Chemical Structure : PK-14105

CAS No.: 107257-28-3

PK-14105 (PK14105)

Catalog No.: PC-42106Not For Human Use, Lab Use Only.

A potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM; attaches covalently and specifically to all the PBS when cardiac membranes are irradiated with this compound under ultraviolet light.

Physicochemical Properties

M.Wt 381.4002
Formula C21H20FN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

3-Isoquinolinecarboxamide, 1-(2-fluoro-5-nitrophenyl)-N-methyl-N-(1-methylpropyl)-

References

1. Doble A, et al. Mol Pharmacol. 1987 Jan;31(1):42-9.

2. Doble A, et al. J Recept Res. 1987;7(1-4):55-70.

3. Skowroński R, et al. Eur J Pharmacol. 1988 Mar 29;148(2):187-93.

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