Chemical Structure : PKC beta II inhibitor H6
CAS No.: 1046787-18-1
Catalog No.: PC-63224Not For Human Use, Lab Use Only.
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM, extracted from patent WO 2008096260 A1 as compound example H6..
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PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM, extracted from patent WO 2008096260 A1 as compound example H6.
M.Wt | 500.623 | |
Formula | C25H37FN8O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
((2S,5R)-2,5-dimethyl-4-((tetrahydro-2H-pyran-4-yl)methyl)piperazin-1-yl)(3-((5-fluoro-2-methylpyrimidin-4-yl)amino)-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)methanone |
1. 3-Aminopyrrolo[3,4-c]pyrazole-5(1H,4H,6H)carboxaldehyde derivatives as PKC inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2008), WO 2008096260 A1 20080814.
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