ROR1 inhibitor 19h

Chemical Structure : ROR1 inhibitor 19h

Catalog No.: PC-23530Not For Human Use, Lab Use Only.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

ROR1 inhibitor 19h is a potent, specfic inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) with SPR KD of 1.1 μM, exhibits antitumor activity in lung cancer and breast cancer cell lines (IC50: 0.36-1.37 μM).
ROR1 inhibitor 19hinduces the apoptosis of tumor cells.
ROR1 inhibitor 19h significantly suppressed tumor growth in a mouse model without obvious toxicity.

Physicochemical Properties

M.Wt	541.61
Formula	C33H27N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((1H-Pyrazolo[3,4-b]pyridin-4-yl)ethynyl)-N-(3-(4-(methoxymethoxy)phenyl)-1-methyl-1H-indol-6-yl)-4-methylbenzamide

References

1. Dongdong Luo, et al. J Med Chem. 2024 Jul 11;67(13):10655-10686.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com