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Chemical Structure : UC1728
CAS No.: 948304-40-3
Catalog No.: PC-35971Not For Human Use, Lab Use Only.
UC1728 (t-TUCB, UC-1728) is a potent and orally available inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 2.0 nM (rabbit liver sEH).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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UC1728 (t-TUCB, UC-1728) is a potent and orally available inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 2.0 nM (rabbit liver sEH).
UC1728 reduces ocular inflammation in a rabbit LPS-induced model of uveitis.
| M.Wt | 438.403 | |
| Formula | C21H21F3N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
trans-4-{4-[3-(4-Trifluoromethoxy-phenyl)-ureido]-cyclohexyloxy}-benzoic acid |
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1. McLellan GJ, et al. J Ocul Biol. 2016 Jan;4(1). doi: 10.13188/2334-2838.1000024.
2. Hwang SH, et al. J Med Chem. 2007 Aug 9;50(16):3825-40.
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